Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062713 | 0.86 | LARS1 (0.42) | LARS1CA12CA1CA2CA4 | |
| SCHEMBL10029348 | 0.84 | CA1 (0.46) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL10029351 | 0.81 | LARS1 (0.47) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL10029346 | 0.81 | LARS1 (0.65) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL9753072 | 0.78 | LARS1 (0.62) | LARS1TERTMMP2MMP9CASR | |
| SCHEMBL10029340 | 0.78 | ALDH1A1 (0.50) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL10029343 | 0.78 | LNPEP (0.48) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL10029356 | 0.77 | HTR6 (0.38) | HTR6CA12CA1CA2CA4 | |
| SCHEMBL10029344 | 0.76 | ALDH1A1 (0.48) | LARS1HTR6CA12CA1CA2 | |
| SCHEMBL10029345 | 0.75 | CA1 (0.55) | HTR6CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106205-B2 | N[S(4-aryl-triazol-3-yl)α-mercaptoacetyl]p-amino benzoic acids as HIV reverse transcriptase inhibitors | ARDEA BIOSCIENCES, INC. (US) | 2012-01-31 | — | — | US | disclosed |