Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697536 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2USP2HTTTSHRHDAC6 | |
| SCHEMBL5562480 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2USP2HTTHDAC6RAB9A | |
| SCHEMBL6816386 | 0.76 | MAPT (0.49) | SMN1; SMN2USP2HTTHDAC6RAB9A | |
| SCHEMBL3360368 | 0.76 | TSHR (0.48) | SMN1; SMN2USP2HTTTSHRALDH1A1 | |
| SCHEMBL9971209 | 0.76 | MEN1 (0.39) | SMN1; SMN2USP2HTTTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL9697076 | 0.76 | TSHR (0.47) | SMN1; SMN2USP2HTTTSHRALDH1A1 | |
| SCHEMBL9732994 | 0.76 | NPC1 (0.46) | SMN1; SMN2USP2HTTTSHRRAB9A | |
| Hydrochloric Acid SCHEMBL9733674 | 0.75 | NPC1 (0.46) | SMN1; SMN2USP2HTTTSHRRAB9A | |
| SCHEMBL9696030 | 0.75 | TNKS (0.42) | SMN1; SMN2USP2HDAC6RAB9AALDH1A1 | |
| SCHEMBL9696959 | 0.75 | TSHR (0.47) | SMN1; SMN2USP2HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |