Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MFN2 | O95140 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752737 | 0.88 | MME (0.42) | MMEMFN2 | |
| SCHEMBL9753244 | 0.87 | MME (0.40) | MMEMFN2 | |
| SCHEMBL9753331 | 0.81 | MME (0.37) | MMEMFN2 | |
| SCHEMBL9753327 | 0.81 | MME (0.37) | MMEMFN2 | |
| SCHEMBL9753159 | 0.76 | MME (0.42) | MMEMFN2 | |
| SCHEMBL9752738 | 0.76 | MFN2 (0.34) | MMEMFN2 | |
| SCHEMBL9753161 | 0.76 | MME (0.42) | MMEMFN2 | |
| SCHEMBL7295956 | 0.74 | MME (0.43) | MME | |
| SCHEMBL7295964 | 0.74 | MME (0.43) | MME | |
| SCHEMBL9753245 | 0.73 | L3MBTL1 (0.32) | MFN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |