Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | MFN2 | O95140 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753327 | 1.00 | MME (0.37) | MMEKMT2AL3MBTL1F7CTSK | |
| SCHEMBL9752737 | 0.87 | MME (0.42) | MMEKMT2AL3MBTL1MFN2 | |
| SCHEMBL9753244 | 0.85 | MME (0.40) | MMEKMT2AL3MBTL1MFN2 | |
| SCHEMBL9753166 | 0.81 | MME (0.38) | MMEMFN2 | |
| SCHEMBL9753159 | 0.76 | MME (0.42) | MMEMFN2 | |
| SCHEMBL9753161 | 0.76 | MME (0.42) | MMEMFN2 | |
| SCHEMBL9752738 | 0.75 | MFN2 (0.34) | MMEKMT2AL3MBTL1F7CTSK | |
| SCHEMBL9753167 | 0.74 | KMT2A (0.36) | KMT2AL3MBTL1F7CTSKCTSS | |
| SCHEMBL7295956 | 0.72 | MME (0.43) | MMEL3MBTL1 | |
| SCHEMBL7295964 | 0.72 | MME (0.43) | MMEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |