SCHEMBL9753247

SCHEMBL9753247

CCCC(=O)OC(C)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27556741 0.98 ALDH1A1 (0.48)
SCHEMBL27473168 0.88 TP53 (0.42)
SCHEMBL20241753 0.83
SCHEMBL706084 0.83 LMNA (0.71)
SCHEMBL13704775 0.82 ALDH1A1 (0.52)
Hydrochloric Acid SCHEMBL26919968 0.81 ALDH1A1 (0.50)
SCHEMBL120124 0.80
SCHEMBL6525191 0.80
SCHEMBL30366016 0.80 LMNA (0.68)
SCHEMBL67893 0.79 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017091617-A1 TRIAZOLE ACC INHIBITORS AND USES THEREOF GILEAD APOLLO, LLC (US) 2017-06-01 WO disclosed
CN-101903386-B Dipeptidyl peptidase-IV inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent LG LIFE SCIENCES LTD 2015-04-22 CN disclosed
CN-102473850-B Device material for hole injection transport layer, ink for forming hole injection transport layer, device having hole injection transport layer, and method for producing same DAINIPPON PRINTING CO LTD 2015-02-11 CN disclosed
CN-102473849-B Device material for hole injection/transport layer, ink for forming hole injection/transport layer, device having hole injection/transport layer, and method for manufacturing same DAINIPPON PRINTING CO LTD 2014-11-05 CN disclosed
CN-101331118-A Pyrazoles useful in the treatment of inflammation BIOLIPOX AB (SE) 2008-12-24 CN disclosed
CN-101151265-A Dipeptidyl peptidase-iv inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent LG LIFE SCIENCES LTD (KR) 2008-03-26 CN disclosed
CN-1913778-A Aminocyclopentyl pyridopyrazinone modulators of chemokine receptor activity MERCK & CO INC (US) 2007-02-14 CN disclosed
CN-1146203-A Pyrimidinyl aryl ketone oximes UNIROYAL CHEM CO INC (US) 1997-03-26 CN disclosed
WO-1991019002-A1 A PROCESS FOR CHIRAL ENRICHMENT OF ASYMMETRIC PRIMARY AMINES CARLBIOTECH LTD. A/S (DK) 1991-12-12 WO disclosed