Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126626 | 0.76 | BRD4 (0.60) | BRD4KMT2AALDH1A1KDM4EMAOA | |
| SCHEMBL17266951 | 0.75 | FLT3 (0.44) | BRD4KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL18947280 | 0.72 | COMT (0.53) | BRD4KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL17266948 | 0.72 | L3MBTL1 (0.44) | BRD4KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL1127326 | 0.71 | BRD4 (0.42) | BRD4ALDH1A1KDM4EGLAGAA | |
| SCHEMBL31585757 | 0.71 | BRD4 (0.50) | BRD4ALDH1A1KDM4EPKMMAPT | |
| SCHEMBL1126585 | 0.71 | BRD4 (0.42) | BRD4KMT2AALDH1A1KDM4EMAPT | |
| Biphenyl SCHEMBL27927789 | 0.66 | ALDH1A1 (0.75) | ALDH1A1MAPTMAOAHSD17B10CYP3A4 | |
| Biphenyl SCHEMBL1557083 | 0.66 | ALDH1A1 (0.75) | ALDH1A1MAPTMAOAHSD17B10CYP3A4 | |
| Biphenyl SCHEMBL547965 | 0.66 | ALDH1A1 (0.90) | ALDH1A1MAPTMAOAHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |