Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 6/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752738 | 0.86 | MFN2 (0.34) | KMT2ACTSKF7L3MBTL1 | |
| SCHEMBL9753245 | 0.84 | L3MBTL1 (0.32) | KMT2AF7L3MBTL1 | |
| SCHEMBL9753327 | 0.74 | MME (0.37) | KMT2ACTSKCTSSKLK5F7 | |
| SCHEMBL9753331 | 0.74 | MME (0.37) | KMT2ACTSKCTSSKLK5F7 | |
| SCHEMBL9752737 | 0.73 | MME (0.42) | KMT2AL3MBTL1 | |
| SCHEMBL9753244 | 0.71 | MME (0.40) | KMT2AL3MBTL1 | |
| SCHEMBL9753166 | 0.69 | MME (0.38) | REN | |
| SCHEMBL9753161 | 0.65 | MME (0.42) | — | |
| SCHEMBL9753159 | 0.65 | MME (0.42) | — | |
| SCHEMBL9753427 | 0.65 | MFN2 (0.42) | KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |