Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 3/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.40 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753343 | 1.00 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CPDE1C | |
| SCHEMBL9753738 | 0.92 | CACNA1F (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CPDE1C | |
| SCHEMBL27365134 | 0.91 | CACNA1F (0.36) | CACNA1FCACNA1DCACNA1SCACNA1CKDM4E | |
| SCHEMBL9753739 | 0.84 | CACNA1F (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CNR1I2 | |
| SCHEMBL9753752 | 0.84 | CACNA1F (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CNR1I2 | |
| SCHEMBL9753709 | 0.84 | HMGCR (0.47) | NR1I2PTGS2CYP2C9 | |
| SCHEMBL27438907 | 0.83 | ALDH1A1 (0.37) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL9753310 | 0.83 | ALDH1A1 (0.37) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL9753282 | 0.83 | CACNA1F (0.46) | CACNA1FCACNA1DCACNA1SCACNA1CPDE1C | |
| SCHEMBL9753682 | 0.77 | MAPK14 (0.40) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |