Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438907 | 1.00 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10GAAALOX15 | |
| SCHEMBL9753687 | 0.91 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10GAAALOX15 | |
| SCHEMBL9753344 | 0.83 | CACNA1F (0.40) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL9753343 | 0.83 | CACNA1F (0.40) | KDM4EHSD17B10CA12CA1CA2 | |
| SCHEMBL9752989 | 0.83 | KDM5B (0.34) | PTGS2KDM5BHMGCR | |
| SCHEMBL9752990 | 0.83 | KDM5B (0.34) | PTGS2KDM5BHMGCR | |
| SCHEMBL9753686 | 0.83 | MAPK14 (0.40) | PTGS2KDM5B | |
| SCHEMBL9753682 | 0.83 | MAPK14 (0.40) | PTGS2KDM5B | |
| SCHEMBL9753226 | 0.82 | MAPK14 (0.39) | PTGS2KDM5B | |
| SCHEMBL9753463 | 0.82 | PTGS2 (0.34) | PTGS2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |