Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 13/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752983 | 0.86 | GCGR (0.43) | GCGRTGFBR1TGFBR2 | |
| SCHEMBL9753345 | 0.83 | PTGS2 (0.33) | GCGRALDH1A1MAPTCYP2C9HPGD | |
| SCHEMBL9753771 | 0.82 | GCGR (0.40) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9753309 | 0.82 | MAPK14 (0.43) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9752952 | 0.81 | GCGR (0.39) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9753336 | 0.81 | MAPK14 (0.42) | GCGRTGFBR1TGFBR2KDM5B | |
| SCHEMBL9753125 | 0.80 | GCGR (0.37) | GCGRKDM5B | |
| SCHEMBL9753351 | 0.79 | PTGS2 (0.32) | KDM5B | |
| SCHEMBL9753651 | 0.79 | ALDH1A1 (0.39) | TGFBR1ALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9753720 | 0.79 | GCGR (0.38) | GCGRTGFBR1TGFBR2KDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |