Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635889 | 0.79 | TRPV1 (0.60) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL4155154 | 0.75 | HTR1A (0.64) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL23015338 | 0.73 | TRPV1 (0.58) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL23205718 | 0.72 | CYP3A4 (0.69) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL27574598 | 0.72 | CNR1 (0.71) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL7649368 | 0.72 | TRPV1 (0.54) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL4410689 | 0.71 | TRPV1 (0.51) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL1585964 | 0.71 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL8645559 | 0.71 | TRPV1 (0.62) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| Vanillyl Alcohol SCHEMBL28864185 | 0.71 | TRPV1 (0.68) | TRPV1CYP1A2CYP3A4CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008738-A1 | COMPOSITIONS AND METHOD FOR TREATING PAINFUL, INFLAMMATORY OR ALLERGIC DISORDERS | CISCO LIMITED PARTNERSHIP (US) | 1991-06-27 | — | — | WO | disclosed |