Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14405112 | 0.91 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL7226867 | 0.89 | ATM (0.55) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL6468821 | 0.89 | ATM (0.55) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL17712999 | 0.87 | SLC6A3 (0.66) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL29451691 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL2504396 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL1223719 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL1223722 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL819337 | 0.84 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2ATM | |
| Hydrochloric Acid SCHEMBL9753140 | 0.82 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |