Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712999 | 0.87 | SLC6A3 (0.66) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL1223719 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATMHDAC4 | |
| SCHEMBL29451691 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATMHDAC4 | |
| SCHEMBL1223722 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATMHDAC4 | |
| SCHEMBL2504396 | 0.85 | HDAC4 (0.61) | SLC6A3SLC6A4SLC6A2ATMHDAC4 | |
| SCHEMBL9753434 | 0.84 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL24434987 | 0.82 | AKR1C3 (0.69) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL3543298 | 0.82 | AKR1C3 (0.69) | SLC6A3SLC6A4SLC6A2ATM | |
| Hydrochloric Acid SCHEMBL9753140 | 0.82 | SLC6A3 (0.53) | SLC6A3SLC6A4SLC6A2ATM | |
| SCHEMBL14405112 | 0.81 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8415496-B2 | Biobased polyesters | Amyris, Inc. | 2013-04-09 | — | — | US | disclosed |
| US-8367859-B2 | Cyclohexane 1,4 carboxylates | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367858-B2 | Terephthalic and trimellitic based acids and carboxylate derivatives thereof | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| WO-2012082727-A1 | BIOBASED POLYAMIDES | Amyris, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012082725-A1 | CONTINUOUS DEHYDROGENATION OF 1,4-CARBOXYLATE SUBSTITUTED CYCLOHEXENES | Amyris, Inc. (US) | 2012-06-21 | — | — | WO | disclosed |
| EP-2443083-A2 | CYCLOHEXENE 1,4-CARBOXYLATES | Amyris, Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288263-A1 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-17 | — | — | US | disclosed |
| WO-2010148081-A2 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148063-A2 | CYCLOHEXENE 1,4-CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148049-A2 | PREPARATION OF TRANS, TRANS MUCONIC ACID AND TRANS, TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148080-A2 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| WO-2010148070-A2 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2010-12-23 | — | — | WO | disclosed |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | CNR2, CBR1, CCR4 | SLC6A3 4680/4885SLC6A4 3260/4885SLC6A2 4350/4885 |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | CBR1, MCM4, CCR4 | SLC6A3 4619/4885SLC6A4 3613/4885SLC6A2 4568/4885 |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | TRIM4, DDT, PICALM | SLC6A3 2177/4885SLC6A4 2796/4885SLC6A2 3198/4885 |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | MUC1, FUT6, ST6GAL1 | SLC6A3 465/4885SLC6A4 779/4885SLC6A2 1700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.