SCHEMBL9753476

SCHEMBL9753476

Nc1nc2c(ncn2[C@H]2C[C@H](O)[C@@H](CO[P](=O)O)O2)c(=O)[nH]1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.68
P2RY2 P41231 1/20 0.57
P2RY4 P51582 1/20 0.57
P2RY6 Q15077 1/20 0.57
TYMP P19971 1/20 0.51
NT5E P21589 2/20 0.49
HINT1 P49773 1/20 0.49
POLA1 P09884 1/20 0.48
PDE3A Q14432 2/20 0.48
PNP P00491 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
HTT P42858 1/20 0.48
PDE4D Q08499 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
GSK3A P49840 2/20 0.46
RPS6KA3 P51812 2/20 0.46
MAPK14 Q16539 2/20 0.46
STING1 Q86WV6 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3148595 0.92 POLB (0.68) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL442294 0.89 POLB (0.71) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL8490891 0.89 POLB (0.71) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL15798769 0.88 POLB (0.70) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL338650 0.88 POLB (0.70) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL16359949 0.88 POLB (0.70) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL15012843 0.88 POLB (0.70) POLBP2RY2P2RY4P2RY6TYMP
SCHEMBL25171429 0.86 POLB (0.82) POLBP2RY2P2RY4P2RY6NT5E
SCHEMBL17117812 0.86 POLB (0.82) POLBP2RY2P2RY4P2RY6NT5E
SCHEMBL48232 0.86 POLB (0.82) POLBP2RY2P2RY4P2RY6NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-87102137-A The improvement relating to antibiotic-producing microorganisms 1987-11-04 CN claimed
WO-1991008213-A1 OLIGORIBONUCLOSIDE AND OLIGODEOXYRIBONUCLEOSIDE BORANOPHOSPHATES BORON BIOLOGICALS, INC. (US) 1991-06-13 WO disclosed
CN-87102137-A The improvement relating to antibiotic-producing microorganisms 1987-11-04 CN disclosed