SCHEMBL9753568

SCHEMBL9753568

CC(C)(C)OC(=O)N[C@@H](CCI)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.49
CTSS P25774 6/20 0.49
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
PPARA Q07869 7/20 0.46
PPARG P37231 6/20 0.46
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
ACE P12821 1/20 0.45
PPARD Q03181 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
IDO1 P14902 1/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21409086 1.00 CTSK (0.49) CTSKCTSSMEN1GAAKMT2A
SCHEMBL346192 1.00 CTSK (0.49) CTSKCTSSMEN1GAAKMT2A
Benzene SCHEMBL28185134 0.97 PPARA (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL4981797 0.92 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A
SCHEMBL4981804 0.92 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A
SCHEMBL7430204 0.92 CTSK (0.52) CTSKCTSSMEN1GAAKMT2A
SCHEMBL1669007 0.89 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL1669009 0.89 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL30788958 0.86 CTSK (0.46) CTSKCTSSMEN1GAAKMT2A
SCHEMBL6745774 0.86 CTSK (0.56) CTSKCTSSMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114929705-A MLL1 inhibitor and anticancer agent 诺华公司 2022-08-19 CN disclosed
EP-2751124-B1 VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION CENTRE NAT RECH SCIENT (FR) 2018-05-16 EP disclosed
WO-1991008737-A2 PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES FISONS PLC (GB) 1991-06-27 WO disclosed