Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801093 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2CYP1A2HPGD | |
| SCHEMBL22621090 | 0.75 | LCK (0.46) | LCK | |
| SCHEMBL24005750 | 0.72 | PIK3C3 (0.46) | ALDH1A1KDM4EADORA3HPGDGLA | |
| SCHEMBL6984523 | 0.71 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL11831966 | 0.70 | POLB (0.44) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL16182550 | 0.69 | PTGS1 (0.42) | ALDH1A1L3MBTL1KDM4ENPSR1HPGD | |
| SCHEMBL26937832 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2NPSR1CYP2C19 | |
| SCHEMBL23213942 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2NPSR1CYP2C19 | |
| SCHEMBL29844628 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP1A2NPSR1CYP2C19 | |
| SCHEMBL7091354 | 0.68 | L3MBTL1 (0.40) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017979-A1 | PROCESS FOR THE PREPARATION OF 2-N-ACYLAMINOPYRIDINES AND 2-AMINOPYRIDINES FROM 5-OXOALKANENITRILE OXIMES | DSM N.V. (NL) | 1991-11-28 | — | — | WO | disclosed |