SCHEMBL9753696

SCHEMBL9753696

O=P(O)(O)c1cnc2ccc(Cl)c(C(O)P(=O)(O)O)n12

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN5 P54829 2/20 0.30
EPHB3 P54753 1/20 0.30
FDPS P14324 1/20 0.30
FDFT1 P37268 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8604889 0.84 EPHB3 (0.33) EPHB3
SCHEMBL9753541 0.82
SCHEMBL8609994 0.77
SCHEMBL8606704 0.77 EPHB3 (0.36) EPHB3
SCHEMBL8608860 0.77 FABP4 (0.33) EPHB3
SCHEMBL8608889 0.76 SMN1; SMN2 (0.36) EPHB3
SCHEMBL8609240 0.74
SCHEMBL9753449 0.74 PGK1 (0.38) FDPS
SCHEMBL8607736 0.74
SCHEMBL8605284 0.73 PTPRA (0.33) EPHB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436831-A2 Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury G.D. Searle & Co. (US) 1991-07-17 EP claimed
WO-1991008211-A1 IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY G.D. SEARLE & CO. (US) 1991-06-13 WO claimed
EP-0436831-A2 Imidazo[1,2-a]pyridinylalkyl compounds for treatment of neurotoxic injury G.D. Searle & Co. (US) 1991-07-17 EP disclosed
WO-1991008211-A1 IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF NEUROTOXIC INJURY G.D. SEARLE & CO. (US) 1991-06-13 WO disclosed