Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.48 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 10/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PROC | P04070 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753713 | 1.00 | MME (0.48) | MMEGHSRCXCR5F2PROC | |
| SCHEMBL9753717 | 1.00 | MME (0.48) | MMEGHSRCXCR5F2PROC | |
| SCHEMBL9753601 | 0.86 | MME (0.43) | MMEGHSRCXCR5 | |
| SCHEMBL9753598 | 0.86 | MME (0.43) | MMEGHSRCXCR5 | |
| SCHEMBL9753945 | 0.77 | MME (0.51) | MMECXCR5 | |
| SCHEMBL9337097 | 0.76 | CYP2C19 (0.36) | MME | |
| SCHEMBL9341047 | 0.76 | CYP2C19 (0.36) | MME | |
| SCHEMBL7368344 | 0.76 | CYP2C19 (0.36) | MME | |
| SCHEMBL7296981 | 0.75 | CYP2C19 (0.35) | MME | |
| SCHEMBL9753816 | 0.75 | MME (0.59) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |