Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753601 | 1.00 | MME (0.43) | MMEGHSRAKT1CXCR5 | |
| SCHEMBL9753713 | 0.86 | MME (0.48) | MMEGHSRCXCR5 | |
| SCHEMBL9753708 | 0.86 | MME (0.48) | MMEGHSRCXCR5 | |
| SCHEMBL9753717 | 0.86 | MME (0.48) | MMEGHSRCXCR5 | |
| SCHEMBL7292686 | 0.85 | AKT1 (0.40) | MMEAKT1 | |
| SCHEMBL9753802 | 0.85 | AKT1 (0.40) | MMEAKT1 | |
| Hydrochloric Acid SCHEMBL7292680 | 0.84 | AKT1 (0.39) | MMEAKT1 | |
| Hydrochloric Acid SCHEMBL9337171 | 0.84 | AKT1 (0.39) | MMEAKT1 | |
| SCHEMBL27349988 | 0.81 | AKT1 (0.41) | AKT1 | |
| SCHEMBL7297122 | 0.77 | MMP1 (0.42) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010644-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |