Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27358634 | 0.90 | RAB9A (0.34) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8657521 | 0.85 | ABL1 (0.37) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8654692 | 0.83 | MEN1 (0.39) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8656102 | 0.77 | ALDH1A1 (0.40) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL27370288 | 0.75 | NPC1 (0.35) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8658267 | 0.74 | KDM4E (0.39) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8657501 | 0.74 | MAPT (0.35) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8654023 | 0.73 | ALDH1A1 (0.35) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| Formanilide SCHEMBL27354436 | 0.73 | ALDH1A1 (0.35) | RAB9AKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL8656564 | 0.71 | TDP1 (0.41) | RAB9AKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009598-A1 | AZAOXINDOLE DERIVATIVES | PFIZER INC. (US) | 1991-07-11 | — | — | WO | disclosed |