Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527711 | 0.92 | PPARG (0.33) | PPARG | |
| SCHEMBL9527727 | 0.89 | AGTR2 (0.41) | — | |
| SCHEMBL9530351 | 0.88 | SLC33A1 (0.38) | — | |
| SCHEMBL9527188 | 0.86 | — | — | |
| SCHEMBL9526534 | 0.85 | — | — | |
| SCHEMBL9525332 | 0.82 | AGTR2 (0.38) | — | |
| SCHEMBL9526362 | 0.82 | AGTR1 (0.44) | — | |
| SCHEMBL9530374 | 0.81 | — | — | |
| SCHEMBL9526753 | 0.80 | — | — | |
| SCHEMBL9527525 | 0.77 | AGTR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | claimed |
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | disclosed |