Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046976 | 0.84 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL6932259 | 0.78 | PPARG (0.48) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL10978263 | 0.75 | LTB4R (0.47) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL9042851 | 0.75 | LTB4R (0.57) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL8777250 | 0.75 | LTB4R (0.57) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL10455677 | 0.73 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| Ethylene SCHEMBL8977854 | 0.73 | LTB4R (0.55) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL2007148 | 0.73 | LTB4R (0.41) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL16576614 | 0.72 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1LTB4RLTB4R2CTSD | |
| SCHEMBL7252527 | 0.71 | BRD4 (0.39) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017989-A1 | ALKOXY-SUBSTITUTED DIHYDROBENZOPYRAN-2-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | G.D. SEARLE & CO. (US) | 1991-11-28 | — | — | WO | disclosed |