Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7163410 | 0.87 | SLC7A5 (0.58) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL7163413 | 0.87 | SLC7A5 (0.58) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL9754294 | 0.85 | CYP1A2 (0.55) | SLC7A5FOLH1 | |
| SCHEMBL2542276 | 0.83 | SLC7A5 (0.56) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL2986794 | 0.83 | SLC7A5 (0.56) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL9332753 | 0.83 | SLC7A5 (0.53) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL28415387 | 0.82 | SLC7A5 (0.51) | SLC7A5ESR1ESR2POLBCYP2D6 | |
| SCHEMBL28415388 | 0.82 | SLC7A5 (0.51) | SLC7A5ESR1ESR2POLBCYP2D6 | |
| SCHEMBL276571 | 0.81 | SLC7A5 (0.55) | SLC7A5CA2CAMK2AESR1ESR2 | |
| SCHEMBL38225 | 0.81 | SLC7A5 (0.55) | SLC7A5CA2CAMK2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015508-A1 | HUMAN SPLENOPENTINE DERIVATIVES AND PROCESS FOR PRODUCING THEM | STIEFEL THOMAS (DE) | 1991-10-17 | — | — | WO | disclosed |