SCHEMBL2542276

SCHEMBL2542276

O=C(O)[C@H](Cc1ccc(O)cc1)N(O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
CA2 P00918 1/20 0.45
CAMK2A Q9UQM7 1/20 0.45
ESR1 P03372 5/20 0.44
ESR2 Q92731 5/20 0.44
TRPV1 Q8NER1 1/20 0.44
POLB P06746 1/20 0.44
FOLH1 Q04609 1/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.43
TAAR1 Q96RJ0 3/20 0.42
SLC6A2 P23975 1/20 0.42
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2986794 1.00 SLC7A5 (0.56) SLC7A5CA2CAMK2AESR1ESR2
Phenol SCHEMBL27420281 0.89 CYP1A2 (0.50) SLC7A5TRPV1POLBFOLH1FNTA
Tyrosine SCHEMBL4908261 0.86 SLC7A5 (0.69) SLC7A5TRPV1
SCHEMBL5352342 0.85 SLC7A5 (0.58) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL157789 0.84 CYP1A2 (0.57) SLC7A5FOLH1
SCHEMBL157788 0.84 CYP1A2 (0.57) SLC7A5FOLH1
SCHEMBL2466759 0.84 CYP1A2 (0.57) SLC7A5FOLH1
SCHEMBL276571 0.83 SLC7A5 (0.55) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL38225 0.83 SLC7A5 (0.55) SLC7A5CA2CAMK2AESR1ESR2
SCHEMBL20494781 0.83 SLC7A5 (0.55) SLC7A5CA2CAMK2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
CN-117343146-A Selaginella tamariscina cyclic heptapeptide compound, and preparation method and application thereof 广西壮族自治区中国科学院广西植物研究所 2024-01-05 CN disclosed
US-20210161672-A1 SCAFFOLD WITH ADHESIVE FOR ARTICULAR CARTILAGE REPAIR HISTOGENICS CORPORATION (US) 2021-06-03 US disclosed
CN-112672717-A Adhesive-bearing scaffold for articular cartilage repair 欧酷根公司 2021-04-16 CN disclosed
EP-3801396-A1 SCAFFOLD WITH ADHESIVE FOR ARTICULAR CARTILAGE REPAIR Histogenics Corporation (US) 2021-04-14 EP disclosed
CN-110655557-A Separation and purification method of pneumocandin B0 serine analogue 浙江医药股份有限公司新昌制药厂 2020-01-07 CN disclosed
EP-2010597-B1 POROUS POLYMER BLEND STRUCTURES UNIV QUEENSLAND (AU) 2015-06-17 EP disclosed
US-20130267483-A1 Hydroxy Acid Complexes for Skin Antiaging, Acne, and Skin Whitening BIODERM RESEARCH (US) 2013-10-10 US disclosed
US-20120189569-A1 Hydroxy Acid Complexes for Skin Renovation and Clarity BIODERM RESEARCH (US) 2012-07-26 US disclosed
WO-2012094708-A1 BONE GRAFT BIOMATERIAL THE UNIVERSITY OF QUEENSLAND (AU) 2012-07-19 WO disclosed
US-6103255-A Porous polymer scaffolds for tissue engineering RUTGERS, THE STATE UNIVERSITY (US) 2000-08-15 US disclosed
EP-0970191-A2 CYTOCHROME P450 MONOOXYGENASES Novartis AG (CH) 2000-01-12 EP disclosed
US-5882851-A DNA MOLECULE CODING FOR A CYTOCHROME P-450 MONOOXYGENASE THAT CATALYZES THE CONVERSION OF AN AMINO ACID TO THE CORRESPONDING N-HYDROXYAMINO ACID AND THE CONVERSION OF SAID N-HYDROXYAMINO ACID TO THE CORRESPONDING OXIME NOVARTIS FINANCE CORPORATION (US) 1999-03-16 US disclosed
WO-1998040470-A2 CYTOCHROME P450 MONOOXYGENASES NOVARTIS AG (CH) 1998-09-17 WO disclosed
EP-0733112-A1 CYTOCHROME P-450 MONOOXYGENASES Novartis AG (CH) 1996-09-25 EP disclosed
WO-1995016041-A1 CYTOCHROME P-450 MONOOXYGENASES CIBA-GEIGY AG (CH) 1995-06-15 WO disclosed
US-5310539-A Paramagnetic rare earth metals, magnetic resonance imaging BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-05-10 US disclosed
EP-0580734-A1 MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-02-02 EP disclosed
WO-1992018166-A1 MELANIN-BASED AGENTS FOR IMAGE ENHANCEMENT BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120189569-A1 Hydroxy Acid Complexes for Skin Renovation and Clarity CUTA, TYR, RBP4 SLC7A5 46/4885CA2 2447/4885CAMK2A 2506/4885
US-20130267483-A1 Hydroxy Acid Complexes for Skin Antiaging, Acne, and Skin Whitening CUTA, TYR, SLC30A6 SLC7A5 24/4885CA2 2397/4885CAMK2A 1595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.