Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754128 | 1.00 | AHCY (0.44) | AHCYHPGDADORA3PAX8TK1 | |
| SCHEMBL9024995 | 0.86 | ADORA3 (0.56) | AHCYHPGDADORA3TK1STING1 | |
| SCHEMBL9024987 | 0.86 | ADORA3 (0.56) | AHCYHPGDADORA3TK1STING1 | |
| SCHEMBL9310744 | 0.76 | ADORA3 (0.61) | HPGDADORA3TK1HPRT1 | |
| SCHEMBL9871642 | 0.76 | ADORA3 (0.61) | HPGDADORA3TK1HPRT1 | |
| SCHEMBL10827165 | 0.76 | AHCY (0.60) | AHCYADORA3TK1STING1HPRT1 | |
| SCHEMBL10827166 | 0.76 | AHCY (0.60) | AHCYADORA3TK1STING1HPRT1 | |
| SCHEMBL9503881 | 0.75 | ADORA3 (0.60) | HPGDADORA3TK1HPRT1 | |
| SCHEMBL9503893 | 0.75 | ADORA3 (0.60) | HPGDADORA3TK1HPRT1 | |
| SCHEMBL9754133 | 0.72 | AHCY (0.49) | AHCYADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018969-A1 | FLUORINATED BIS(HYDROXYMETHYL)CYCLOBUTYL PURINES AND PYRIMIDINES | E.R. SQUIBB & SONS, INC. (US) | 1991-12-12 | — | — | WO | disclosed |