Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10620080 | 0.85 | CTSL (0.52) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL18428130 | 0.83 | CTSK (0.42) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28511485 | 0.83 | CYP2D6 (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28216119 | 0.83 | CTSK (0.42) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL28511486 | 0.83 | CYP2D6 (0.47) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL20063688 | 0.82 | SMN1; SMN2 (0.41) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL15456301 | 0.82 | SMN1; SMN2 (0.41) | CTSKCTSSCTSLCTSBCA1 | |
| SCHEMBL13523650 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL13523719 | 0.81 | CTSK (0.56) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL15797149 | 0.80 | CA1 (0.42) | CTSKCTSSCTSLCTSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |