Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.43 |
| ▸ | SGPL1 | O95470 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754192 | 1.00 | HCRTR2 (0.43) | HCRTR2SGPL1S1PR1RAB9ASPHK1 | |
| SCHEMBL15581072 | 0.86 | HCRTR2 (0.43) | HCRTR2SGPL1S1PR1KDM1AHTR2A | |
| SCHEMBL15061084 | 0.84 | HCRTR2 (0.33) | HCRTR2SGPL1S1PR1RAB9ASPHK1 | |
| SCHEMBL13402101 | 0.83 | RAB9A (0.40) | RAB9A | |
| SCHEMBL9625016 | 0.83 | HCRTR2 (0.35) | HCRTR2SGPL1S1PR1RAB9ALIPC | |
| SCHEMBL9625010 | 0.83 | HCRTR2 (0.35) | HCRTR2SGPL1S1PR1RAB9ALIPC | |
| SCHEMBL15061053 | 0.83 | GPR119 (0.35) | HCRTR2SGPL1S1PR1RAB9ASPHK1 | |
| SCHEMBL15061047 | 0.82 | KDM1A (0.47) | HCRTR2SGPL1S1PR1RAB9ASPHK1 | |
| SCHEMBL15061082 | 0.82 | KDM1A (0.47) | HCRTR2SGPL1S1PR1RAB9ASPHK1 | |
| SCHEMBL27897507 | 0.82 | HCRTR2 (0.47) | HCRTR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015450-A1 | PHENYL CYCLOHEXANES AND LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-10-17 | — | — | WO | disclosed |