Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.71 |
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | CTSD | P07339 | 4/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835847 | 0.94 | PSENEN (0.71) | PSENENCTSSCTSKCTSDREN | |
| SCHEMBL7104010 | 0.88 | PSENEN (0.59) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL245495 | 0.88 | PSENEN (0.62) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL2548149 | 0.88 | PSENEN (0.59) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL1486223 | 0.88 | PSENEN (0.62) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL17137934 | 0.88 | PSENEN (0.59) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL1486221 | 0.88 | PSENEN (0.62) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL23080124 | 0.88 | PSENEN (0.64) | PSENENCTSSCTSKCTSDREN | |
| SCHEMBL22068619 | 0.87 | CTSS (0.65) | PSENENCTSSCTSKCTSDCA2 | |
| SCHEMBL22068618 | 0.87 | CTSS (0.65) | PSENENCTSSCTSKCTSDCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |