Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651568 | 0.92 | — | — | |
| SCHEMBL9754421 | 0.87 | — | — | |
| SCHEMBL5275955 | 0.82 | EPHX1 (0.46) | EPHX1ATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9708685 | 0.80 | EPHX1 (0.44) | EPHX1ATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27991206 | 0.78 | EPHX1 (0.60) | EPHX1ATMSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23042508 | 0.77 | EPHX1 (0.41) | EPHX1ATMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2145781 | 0.77 | EPHX1 (0.58) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4275457 | 0.77 | EPHX1 (0.46) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28223521 | 0.76 | BCL2A1 (0.35) | — | |
| SCHEMBL11373290 | 0.76 | CES2 (0.44) | EPHX1ATMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109629026-A | A kind of cellulose melt spun fibre and preparation method thereof with durable antibiotic performance | 东华大学 | 2019-04-16 | — | — | CN | claimed |
| CN-105431422-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2019-08-30 | — | — | CN | disclosed |
| CN-109988186-A | Beta-lactamase inhibitor | 维纳拓尔斯制药公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109629026-A | A kind of cellulose melt spun fibre and preparation method thereof with durable antibiotic performance | 东华大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106687465-B | β -lactamase inhibitor | 维纳拓尔斯制药公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109456324-A | New isoindoline or isoquinoline compound, preparation method and the Pharmaceutical composition containing them | 法国施维雅药厂 | 2019-03-12 | — | — | CN | disclosed |
| CN-108137581-A | novel imidazo [4,5-b ] pyridine derivatives as dual DYRK1/C L K1 inhibitors | 法国施维雅药厂 | 2018-06-08 | — | — | CN | disclosed |
| CN-104603105-B | It is used as the formamide or nitrogenous 5 circle heterocycles of sulfonamide substitutions of orphan nuclear receptor ROR gamma modulators | 菲尼克斯药品股份公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-107108485-A | KCNQ 2-5 channel activator | 小野药品工业株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-106687465-A | Beta-lactamase inhibitors | 维纳拓尔斯制药公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-106474112-A | A kind of pharmaceutical composition of anti-acute myocardial ischemia coronary heart disease and its application | 段占娥 | 2017-03-08 | — | — | CN | disclosed |
| CN-106061980-A | Thienopyrimidines as MKNK1 and MKNK2 Inhibitors | 拜耳制药股份公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-105228620-A | N-acyl-N' - (pyridin-2-yl) ureas and analogs exhibiting anti-cancer and anti-proliferative activity | DECIPHERA PHARMACEUTICALS LLC | 2016-01-06 | — | — | CN | disclosed |
| CN-101553224-A | Novel imidazothiazoles and imidazoxazoles | ABBOTT LAB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-1326519-C | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2007-07-18 | — | — | CN | disclosed |
| CN-1602191-A | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase | NOVO NORDISK AS (DK) | 2005-03-30 | — | — | CN | disclosed |
| CN-1056374-C | Tricyclic diazepine vasopression antagonists | AMERICAN CYANAMID CO (US) | 2000-09-13 | — | — | CN | disclosed |
| CN-1039908-C | Tricyclic diaza * vasopressin antagonists and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1998-09-23 | — | — | CN | disclosed |
| US-5032588-A | Non-steroidal antiinflammatory | ABBOTT LABORATORIES (US) | 1991-07-16 | — | — | US | disclosed |
| WO-1991008744-A1 | THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS | ABBOTT LABORATORIES (US) | 1991-06-27 | — | — | WO | disclosed |