Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530304 | 0.89 | EDNRA (0.35) | AGTR2AGTR1EDNRA | |
| SCHEMBL9526639 | 0.88 | — | — | |
| SCHEMBL9527525 | 0.85 | AGTR1 (0.38) | AGTR2AGTR1 | |
| SCHEMBL9527008 | 0.83 | AGTR2 (0.50) | AGTR2AGTR1 | |
| SCHEMBL9526538 | 0.82 | AGTR2 (0.39) | AGTR2AGTR1 | |
| SCHEMBL9526460 | 0.81 | AGTR2 (0.42) | AGTR2AGTR1 | |
| SCHEMBL9526466 | 0.80 | — | — | |
| SCHEMBL9526413 | 0.79 | AGTR1 (0.39) | AGTR2AGTR1 | |
| SCHEMBL9151051 | 0.79 | — | — | |
| SCHEMBL9530005 | 0.79 | AGTR2 (0.40) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991015479-A1 | SUBSTITUTED PYRAZOLES, ISOXAZOLES AND ISOTHIAZOLES | MERCK & CO., INC. (US) | 1991-10-17 | — | — | WO | disclosed |