Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536983 | 0.88 | KDM4E (0.45) | KDM4EALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL9535021 | 0.87 | GSK3B (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9754429 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL6336468 | 0.80 | HSD17B10 (0.49) | KDM4EALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL9538652 | 0.78 | TDP1 (0.54) | KDM4EALDH1A1HPGDGAAALPL | |
| SCHEMBL7276461 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6336732 | 0.78 | HSD17B10 (0.47) | KDM4EALDH1A1NR4A1NR4A2NR4A3 | |
| SCHEMBL9536899 | 0.78 | CDC25B (0.42) | KDM4EALDH1A1HPGDCDC25BGAA | |
| SCHEMBL9535167 | 0.77 | KDM4E (0.42) | KDM4EGAAALPLLDHAPDE10A | |
| SCHEMBL25148779 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |