Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9539842 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL9754384 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1RXFP1GAASMN1; SMN2 | |
| SCHEMBL9534817 | 0.79 | TDP1 (0.45) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9535637 | 0.78 | PTGER3 (0.39) | KDM4EALDH1A1GAASMN1; SMN2CDC25B | |
| SCHEMBL9536127 | 0.75 | KDM4E (0.37) | KDM4EALDH1A1GAASMN1; SMN2CDC25B | |
| SCHEMBL4431905 | 0.75 | KDM4E (0.69) | KDM4EALDH1A1RXFP1GAASMN1; SMN2 | |
| SCHEMBL4074628 | 0.74 | KDM4E (1.00) | KDM4EALDH1A1RXFP1GAASMN1; SMN2 | |
| SCHEMBL7276461 | 0.74 | KDM4E (0.63) | KDM4EALDH1A1RXFP1GAASMN1; SMN2 | |
| SCHEMBL9536884 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL22656935 | 0.73 | SOS1 (0.62) | KDM4EALDH1A1RXFP1SOS1WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | claimed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |