Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 4/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31744319 | 0.89 | ACE (0.64) | RENACECTSSCTSKCTSL | |
| SCHEMBL638877 | 0.89 | ACE (0.68) | RENACECTSSCTSKCTSL | |
| SCHEMBL495795 | 0.89 | ACE (0.68) | RENACECTSSCTSKCTSL | |
| SCHEMBL495794 | 0.89 | ACE (0.68) | RENACECTSSCTSKCTSL | |
| SCHEMBL28980533 | 0.87 | KLK5 (0.62) | RENACECTSSCTSKCTSL | |
| SCHEMBL28980600 | 0.87 | KLK5 (0.62) | RENACECTSSCTSKCTSL | |
| SCHEMBL11518112 | 0.86 | REN (0.63) | RENACECTSSCTSKCTSL | |
| SCHEMBL17350165 | 0.85 | ACE (0.64) | RENACECTSSCTSKCTSL | |
| SCHEMBL9754234 | 0.85 | CTSL (0.57) | CTSSCTSKCTSLCTSBPSMB1 | |
| SCHEMBL7450821 | 0.83 | ACE (0.61) | RENACECTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |