Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536814 | 0.80 | KDM4E (0.45) | KDM4ETHRBAHRMAOATOP2A | |
| SCHEMBL9754508 | 0.74 | KDM4E (0.52) | KDM4ETHRBAHRDYRK1AMAPT | |
| SCHEMBL9754535 | 0.73 | AHR (0.41) | KDM4EAHRMAOAMAOBFTO | |
| SCHEMBL28087516 | 0.70 | PADI4 (0.44) | KDM4ETHRBAHRMAOAMAOB | |
| SCHEMBL9779012 | 0.69 | AHR (0.46) | KDM4ETHRBAHRMAOAMAOB | |
| SCHEMBL9843531 | 0.68 | MGAM (0.41) | KDM4ETHRBMAOAMAOBTOP2A | |
| SCHEMBL5226658 | 0.68 | KDM4E (0.53) | KDM4ETHRBMAOAMAOBTOP2A | |
| SCHEMBL27290368 | 0.67 | AHR (0.47) | KDM4EAHRMAOAMAOBFTO | |
| SCHEMBL9754638 | 0.67 | MAOA (0.41) | KDM4ETHRBAHRMAOAMAOB | |
| SCHEMBL31332447 | 0.66 | KDM4E (0.51) | KDM4ETHRBAHRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |