Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778972 | 0.80 | KDM4E (0.45) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9754638 | 0.77 | MAOA (0.41) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9754514 | 0.76 | CSNK2A1 (0.47) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9843460 | 0.74 | GAA (0.38) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9102343 | 0.72 | ERN1 (0.51) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL11823570 | 0.72 | MAOA (0.50) | KDM4EMEN1RAB9AKMT2AMAOA | |
| SCHEMBL9754603 | 0.70 | ALDH1A1 (0.45) | GAAKDM4EMEN1RAB9AKMT2A | |
| SCHEMBL9536657 | 0.68 | MAOA (0.45) | MGAMGAASIMGAM2KDM4E | |
| SCHEMBL9843654 | 0.68 | SLC2A1 (0.35) | MGAMGAASIMGAM2ESR2 | |
| SCHEMBL9754461 | 0.68 | KDM4E (0.42) | KDM4ETHRBESR2TOP2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |