SCHEMBL9754476

SCHEMBL9754476

COc1nc(Oc2cccc(-c3ccccc3)c2C(=O)O)nc(OC)c1Cl

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
FABP4 P15090 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9046270 0.88 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL9053287 0.84 CYP2C9 (0.40) CA12CA1CA2CA7CA9
SCHEMBL9215334 0.82 CYP1A2 (0.52) ALDH1A1SMN1; SMN2NPSR1
SCHEMBL9754474 0.81 CYP2C9 (0.44) CA12CA1CA2CA7CA9
SCHEMBL9318890 0.80 EDNRB (0.50) ALDH1A1CA12CA1CA2CA7
SCHEMBL9045391 0.79 PTGDR2 (0.39) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL4002652 0.77 CA12 (0.69) ALDH1A1CA12CA1CA2CA7
SCHEMBL30536599 0.77 CA12 (0.69) ALDH1A1CA12CA1CA2CA7
SCHEMBL9129900 0.76 LMNA (0.46) NPSR1
SCHEMBL9047372 0.75 GCK (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013065-A1 6-ARYL-2-SUBSTITUTED BENZOIC ACID HERBICIDES FMC CORPORATION (US) 1991-09-05 WO disclosed