Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754527 | 0.81 | SLC2A1 (0.38) | GAAMGAMSIMGAM2ESR2 | |
| Hydrochloric Acid SCHEMBL9754576 | 0.80 | SLC2A1 (0.37) | GAAMGAMSIMGAM2ESR2 | |
| SCHEMBL9843460 | 0.77 | GAA (0.38) | GAAMGAMSIMGAM2ESR2 | |
| SCHEMBL9754638 | 0.76 | MAOA (0.41) | GAAMGAMSIMGAM2ESR2 | |
| SCHEMBL9754586 | 0.73 | MAOA (0.52) | MAOBMAOAKDM4EMAPTHPGD | |
| SCHEMBL2954355 | 0.71 | MAOA (0.47) | GAAMGAMSIMGAM2MAOB | |
| SCHEMBL11823570 | 0.67 | MAOA (0.50) | MAOBMAOAKDM4EMAPTHPGD | |
| SCHEMBL11310801 | 0.67 | KDM4E (0.33) | GAAMAOBKDM4EMAPTL3MBTL1 | |
| SCHEMBL13250608 | 0.67 | MAOA (0.48) | GAAMAOBMAOAKDM4EMAPT | |
| SCHEMBL24751333 | 0.67 | GPR55 (0.47) | MAOAKDM4EMAPTHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |