Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534290 | 0.82 | KDM4E (0.45) | KDM4EL3MBTL1GAAALPLGSK3B | |
| SCHEMBL9534012 | 0.80 | KDM4E (0.43) | KDM4EL3MBTL1GAAALPLGSK3B | |
| SCHEMBL17223272 | 0.79 | ALDH1A1 (0.49) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL9149933 | 0.78 | ALDH1A1 (0.36) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL12229775 | 0.76 | HPGD (0.54) | KDM4EHPGDLMNAALDH1A1L3MBTL1 | |
| SCHEMBL9536899 | 0.71 | CDC25B (0.42) | KDM4EHPGDALDH1A1MAPTNPSR1 | |
| SCHEMBL17489008 | 0.70 | ALDH1A1 (0.59) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL17537482 | 0.70 | ALDH1A1 (0.59) | LMNAALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9534911 | 0.69 | ALDH1A1 (0.40) | KDM4EHPGDLMNAALDH1A1MAPT | |
| SCHEMBL9535021 | 0.69 | GSK3B (0.47) | KDM4EHPGDALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |