Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534290 | 0.89 | KDM4E (0.45) | KDM4EALPLGAATYMPPIM1 | |
| SCHEMBL9754618 | 0.80 | KDM4E (0.41) | KDM4EALPLGAATYMPPDE10A | |
| SCHEMBL9536127 | 0.73 | KDM4E (0.37) | KDM4EGAA | |
| SCHEMBL9754384 | 0.72 | KDM4E (0.59) | KDM4EALPLGAATYMPPDE10A | |
| SCHEMBL9535021 | 0.71 | GSK3B (0.47) | KDM4EALPLGAATYMPPIM1 | |
| Phosphoric Acid SCHEMBL29911372 | 0.71 | ACP3 (0.55) | KDM4EALPLGAAACP3POLB | |
| Phosphoric Acid SCHEMBL547015 | 0.71 | ACP3 (0.55) | KDM4EALPLGAAACP3POLB | |
| SCHEMBL9536983 | 0.70 | KDM4E (0.45) | KDM4EALPLGAATYMPPIM1 | |
| SCHEMBL9754547 | 0.70 | MCL1 (0.55) | KDM4EALPLGAATYMPPIM1 | |
| SCHEMBL9538652 | 0.69 | TDP1 (0.54) | KDM4EALPLGAATYMPPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |