Butane

Butane

SCHEMBL9754798

CCCC.O=C(O)S.O=C(O)S.O=C(O)S.O=C(O)S

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC3 O15379 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
TDP1 Q9NUW8 4/20 0.40
CHRM1 P11229 1/20 0.40
AKR1A1 P14550 1/20 0.40
CHRM3 P20309 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
AKR1B1 P15121 1/20 0.40
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL19990800 0.83
Butane SCHEMBL29197512 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL21633593 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL28409881 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL40275 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL1165212 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL28896048 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL1329645 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8
Butane SCHEMBL1716773 0.82
Butane SCHEMBL2650732 0.82 FFAR3 (0.54) FFAR3HDAC1HDAC2HDAC3HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013551-A1 PELLETIZED THIOCARBONATES FOR SOIL TREATMENT UNION OIL COMPANY OF CALIFORNIA (US) 1991-09-19 WO disclosed