SCHEMBL9754803

SCHEMBL9754803

OCCOc1cccc(C=Cc2nc3cc(F)ccc3s2)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 1/20 0.46
ATP4A P20648 15/20 0.42
ATP4B P51164 15/20 0.42
SYK P43405 1/20 0.38
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9338942 0.81 KAT8 (0.50) KAT8
SCHEMBL9338937 0.81 KAT8 (0.50) KAT8
SCHEMBL9515591 0.80 ATP4A (0.55) ATP4AATP4B
SCHEMBL9515581 0.80 ATP4A (0.55) ATP4AATP4B
SCHEMBL22472257 0.79 MEN1 (0.53) ATP4AATP4B
SCHEMBL9335180 0.77 KAT8 (0.50) KAT8
SCHEMBL9335002 0.77 KAT8 (0.53) KAT8
SCHEMBL9334994 0.77 KAT8 (0.53) KAT8
SCHEMBL9335185 0.77 KAT8 (0.50) KAT8
SCHEMBL9385684 0.75 KAT8 (0.49) KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991017163-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER INC. (US) 1991-11-14 WO disclosed