SCHEMBL9515591

SCHEMBL9515591

OCCCCOc1cccc(C=Cc2nc3ccccc3s2)c1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 20/20 0.55
ATP4B P51164 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515581 1.00 ATP4A (0.55) ATP4AATP4B
SCHEMBL22472257 0.88 MEN1 (0.53) ATP4AATP4B
SCHEMBL9518047 0.84 CYSLTR2 (0.57) ATP4AATP4B
SCHEMBL9518053 0.84 CYSLTR2 (0.57) ATP4AATP4B
SCHEMBL9516841 0.82 CYSLTR2 (0.67) ATP4AATP4B
SCHEMBL9516834 0.82 CYSLTR2 (0.67) ATP4AATP4B
SCHEMBL9754803 0.80 KAT8 (0.46) ATP4AATP4B
SCHEMBL9515980 0.78 CYSLTR2 (0.53) ATP4AATP4B
SCHEMBL9515993 0.78 CYSLTR2 (0.53) ATP4AATP4B
SCHEMBL9514854 0.78 SNCA (0.64) ATP4AATP4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0219436-B1 Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients MITSUBISHI CHEM IND (JP) 1993-12-22 EP disclosed
US-4902700-A Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients MITSUBISHI KASEI CORPORATION (JP) 1990-02-20 US disclosed
EP-0219436-A2 Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients MITSUBISHI KASEI CORPORATION (JP) 1987-04-22 EP disclosed