SCHEMBL9754813

SCHEMBL9754813

CCCc1nc2ccc(OC(=O)O)cc2n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 14/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9195684 0.84 EDNRA (0.55) PPARG
SCHEMBL6545316 0.84 AGTR1 (0.49)
SCHEMBL9194632 0.83 PPARG (0.62) PPARG
SCHEMBL9193758 0.83 PPARG (0.49) PPARG
SCHEMBL8788997 0.83 AGTR1 (0.58) PPARG
SCHEMBL6546048 0.82 AGTR1 (0.48) PPARG
SCHEMBL7304644 0.81 PPARG (0.53) PPARG
SCHEMBL7306523 0.81 PPARG (0.51) PPARG
SCHEMBL9197073 0.81 AGTR1 (0.53)
SCHEMBL8789968 0.81 PPARG (0.49) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991013063-A1 NEW BENZIMIDAZOLE DERIVATIVES, METHOD FOR PREPARING THEM AND THEIR PHARMACEUTICAL USE SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1991-09-05 WO disclosed