Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 8/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6545316 | 0.91 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7907438 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL6545442 | 0.88 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL3840808 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL6545554 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL6546670 | 0.86 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8736122 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7907474 | 0.83 | PPARG (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL7443225 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9193758 | 0.83 | PPARG (0.49) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019048-B1 | USE OF AN ANGIOTENSIN II RECEPTOR ANTAGONIST FOR THE PREPARATION OF DRUGS TO INCREASE THE SURVIVAL RATE OF RENAL TRANSPLANT PATIENTS | MERCK SHARP DOHME ITALIA S P A (IT) | 2004-01-21 | — | — | EP | claimed |
| EP-0324377-B1 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | DU PONT (US) | 1997-04-16 | — | — | EP | claimed |