Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422754 | 0.81 | NOTUM (0.44) | ALDH1A1 | |
| SCHEMBL7216579 | 0.77 | TLR8 (0.41) | TLR8ALDH1A1KDM4ELMNAHPGD | |
| Hydrochloric Acid SCHEMBL7631242 | 0.76 | HTR2A (0.40) | TLR8ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9532236 | 0.76 | NOTUM (0.41) | ALDH1A1TLR7APLNR | |
| SCHEMBL9856773 | 0.73 | ALDH1A1 (0.46) | TLR8ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9537616 | 0.71 | NOTUM (0.46) | ALDH1A1APLNR | |
| SCHEMBL9530798 | 0.71 | ALDH1A1 (0.41) | TLR8ALDH1A1HTR2AHTR2CSLC6A4 | |
| SCHEMBL6968208 | 0.71 | TLR8 (0.45) | TLR8ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL7270020 | 0.70 | ALDH1A1 (0.41) | TLR8ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL9422896 | 0.69 | NOTUM (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | disclosed |