Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530798 | 0.85 | ALDH1A1 (0.41) | NOTUMALDH1A1TLR7 | |
| SCHEMBL9422754 | 0.84 | NOTUM (0.44) | NOTUMALDH1A1AGTR1AGTR2 | |
| SCHEMBL9537616 | 0.81 | NOTUM (0.46) | NOTUMALDH1A1APLNRAGTR1AGTR2 | |
| SCHEMBL9422896 | 0.78 | NOTUM (0.44) | NOTUMALDH1A1AGTR1AGTR2 | |
| SCHEMBL9754909 | 0.76 | TLR8 (0.37) | ALDH1A1APLNRTLR7 | |
| SCHEMBL9856773 | 0.72 | ALDH1A1 (0.46) | ALDH1A1APLNR | |
| SCHEMBL6968208 | 0.70 | TLR8 (0.45) | ALDH1A1APLNRAGTR1AGTR2 | |
| SCHEMBL27461046 | 0.70 | ALDH1A1 (0.42) | ALDH1A1APLNR | |
| SCHEMBL7270020 | 0.69 | ALDH1A1 (0.41) | ALDH1A1APLNRAGTR1AGTR2 | |
| SCHEMBL7270215 | 0.69 | AGTR1 (0.47) | ALDH1A1APLNRAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | disclosed |