Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614621 | 0.98 | KDM4E (0.41) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL3924183 | 0.98 | KDM4E (0.41) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL6710510 | 0.95 | GABRP (0.41) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL21439468 | 0.87 | SMN1; SMN2 (0.37) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL31046847 | 0.87 | SMN1; SMN2 (0.37) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL1082565 | 0.86 | HCAR2 (0.41) | KDM4EMEN1KMT2ALMNACYP3A4 | |
| SCHEMBL22202360 | 0.86 | KDM4E (0.39) | KDM4ELMNACYP3A4GABRPGABRD | |
| SCHEMBL3916646 | 0.84 | RARB (0.43) | KDM4EMEN1KMT2AGABRPGABRD | |
| SCHEMBL8624574 | 0.84 | RARB (0.43) | KDM4EMEN1KMT2AGABRPGABRD | |
| SCHEMBL3604705 | 0.84 | RARB (0.43) | KDM4EMEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005771-A1 | LIPOPHILIC ACYLPYRAZINAMIDE PRODRUGS | SCHREIER HANS (US) | 1991-05-02 | — | — | WO | claimed |
| WO-1991005771-A1 | LIPOPHILIC ACYLPYRAZINAMIDE PRODRUGS | SCHREIER HANS (US) | 1991-05-02 | — | — | WO | disclosed |
| WO-1991005771-A1 | LIPOPHILIC ACYLPYRAZINAMIDE PRODRUGS | SCHREIER HANS (US) | 1991-05-02 | — | — | WO | disclosed |