Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45861 | 0.75 | GABRA1 (0.68) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL12610344 | 0.74 | KDM4E (0.41) | GABRA1GABRB2HSD17B3FEN1ESR1 | |
| SCHEMBL29032120 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL27854994 | 0.71 | CYP3A4 (0.47) | GABRA1GABRB2ALDH1A1HPGDMAPK1 | |
| SCHEMBL16527810 | 0.69 | GABRA1 (0.59) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL372102 | 0.69 | PIM1 (0.43) | ESR1ESR2ALDH1A1HPGDGAA | |
| SCHEMBL3949360 | 0.68 | CYP1A2 (0.47) | GABRA1GABRB2 | |
| SCHEMBL3952889 | 0.68 | GABRA1 (0.64) | GABRA1GABRB2ALDH1A1HTT | |
| SCHEMBL4961265 | 0.67 | GABRA1 (0.56) | GABRA1GABRB2FEN1ESR1ESR2 | |
| SCHEMBL29719025 | 0.67 | GABRA1 (0.56) | GABRA1GABRB2ESR1ESR2PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005605-A1 | CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS | KOSAK KENNETH M (US) | 1991-05-02 | — | — | WO | disclosed |
| WO-1991002040-A1 | CYCLODEXTRIN LABELS FOR NUCLEIC ACID AND BIOCHEMICAL ANALYSIS | KOSAK KENNETH M (US) | 1991-02-21 | — | — | WO | disclosed |