Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9363421 | 0.91 | SYK (0.37) | SYKDDB1CRBNCTSL | |
| SCHEMBL9755072 | 0.87 | SYK (0.39) | SYKDDB1CRBNCTSLALDH1A1 | |
| SCHEMBL9366379 | 0.87 | SYK (0.39) | SYKDDB1CRBNCTSLALDH1A1 | |
| SCHEMBL9755074 | 0.87 | SYK (0.39) | SYKDDB1CRBNCTSLALDH1A1 | |
| SCHEMBL7450142 | 0.86 | MME (0.47) | SYKMME | |
| SCHEMBL6807982 | 0.84 | MME (0.45) | SYKDDB1CRBNMME | |
| SCHEMBL9363400 | 0.79 | KMT2A (0.36) | DDB1CRBNCTSLALDH1A1 | |
| SCHEMBL4992578 | 0.78 | SLC15A1 (0.43) | SYKCTSLALDH1A1MME | |
| SCHEMBL7364029 | 0.76 | SYK (0.51) | SYKCTSLALDH1A1MME | |
| SCHEMBL16347929 | 0.75 | ALDH1A1 (0.45) | DDB1CRBNCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013054-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1991-09-05 | — | — | WO | disclosed |