Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.50 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | CTSE | P14091 | 3/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554576 | 0.81 | REN (0.49) | RENCTSEPSEN1PSEN2APH1B | |
| SCHEMBL7397021 | 0.78 | REN (0.51) | RENCTSDCTSE | |
| SCHEMBL9554830 | 0.77 | REN (0.48) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9555326 | 0.75 | REN (0.51) | REN | |
| SCHEMBL9727829 | 0.73 | REN (0.48) | REN | |
| SCHEMBL7368054 | 0.73 | REN (0.41) | RENCTSDCTSE | |
| SCHEMBL9554791 | 0.72 | REN (0.49) | RENCTSE | |
| SCHEMBL7369375 | 0.71 | REN (0.49) | RENCTSDCTSE | |
| SCHEMBL7331904 | 0.71 | REN (0.66) | REN | |
| SCHEMBL7363064 | 0.71 | REN (0.59) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006561-A1 | METHOD FOR TREATING HIV AND OTHER RETROVIRUSES AND COMPOUNDS USEFUL THEREFOR | THE UPJOHN COMPANY (US) | 1991-05-16 | — | — | WO | claimed |